Faculty
Dr. H. Lee Woodcock
Professor
Contact
Office: IDRB 204
Phone: 813/974-9239
Lab: IDRB 204
Email
Education
B.S., Appalachian State University, 1998
Ph.D., University of Georgia, 2003
Lenfant Biomedical Fellow (National Heart, Lung, and Blood Institute, NIH), 2008
Career Transition Award (K22, National Heart, Lung, and Blood Institute, NIH), 2009
Research
Computational Chemistry / Biophysical Chemistry
The research in our lab focuses on the development and application of molecular simulation
techniques to solve interesting problems that exist at the interface of chemistry,
biology and medicine. I currently have two main areas of interest:
1.Examination of structure, dynamics, and mechanism by simulation. Specifically, this
focuses on two main areas; examination of antibiotic and inhibitor resistance mechanisms
with hybrid quantum mechanical and molecular mechanical (QM/MM) methods and elucidation
of carbohydrate structure and dynamics as related to energy production.
2.Development of new simulation and analysis techniques. This area primarily focuses
on multi-scale modeling methods, techniques for computing free energies of enzymatically
catalyzed reactions, and methods for probing the normal modes of complex systems.